Mammalian Target of Rapamycin: Hitting the Bull's-Eye for Neurological Disorders
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چکیده
منابع مشابه
Mammalian Target of Rapamycin: Hitting the Bull's-Eye for Neurological Disorders
The mammalian target of rapamycin (mTOR) and its associated cell signaling pathways have garnered significant attention for their roles in cell biology and oncology. Interestingly, the explosion of information in this field has linked mTOR to neurological diseases with promising initial studies. mTOR, a 289 kDa serine/threonine protein kinase, plays an important role in cell growth and prolifer...
متن کاملTargeting or Target Group: Hitting the Bulls-eye
The aim behind every organization is to manufacture products which would fulfill the needs of a potential customer. Organization do plenty of research for making new innovative products, focus on product / service quality, train their resources and assess their financial resources etc. These things are very critical in determining the efforts and journey of any product. But above all, there is ...
متن کاملTargeting or Target Group: Hitting the Bulls-eye
The aim behind every organization is to manufacture products which would fulfill the needs of a potential customer. Organization do plenty of research for making new innovative products, focus on product / service quality, train their resources and assess their financial resources etc. These things are very critical in determining the efforts and journey of any product. But above all, there is ...
متن کاملMammalian target of rapamycin (mTOR) pathways in neurological diseases.
The mammalian target of rapamycin (mTOR) pathway is an essential cellular signaling pathway involved in a number of important physiological functions, including cell growth, proliferation, metabolism, protein synthesis, and autophagy. Dysregulation of the mTOR pathway has been implicated in the pathophysiology of a number of neurological diseases. Hyperactivation of the mTOR pathway, leading to...
متن کاملMammalian target of rapamycin inhibition.
The mammalian target of rapamycin (mTOR) is a serine/threonine kinase that has been increasingly recognized as key to the regulation of cell growth and proliferation. mTOR either directly or indirectly regulates translation initiation, actin organization, tRNA synthesis, ribosome biogenesis, and many other key cell maintenance functions, including protein degradation and transcription functions...
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ژورنال
عنوان ژورنال: Oxidative Medicine and Cellular Longevity
سال: 2010
ISSN: 1942-0900,1942-0994
DOI: 10.4161/oxim.3.6.14787